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Kerr, J
Glutathione Precursors NAC provides cysteine, while glycine supplies another amino acid needed to synthesize glutathione
Studies have shown that AMPK upregulates fatty acid oxidation genes (e.g., carnitine palmitoyl transferase 1 (CPT1) and peroxisome proliferator-activated receptor alpha (PPAR)) and downregulates synthesis genes (e.g., fatty acid synthase (FAS) and sterol regulatory element-binding protein 1c (SREBP-1c)) [67]
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Mice in the DMM + ferroastatin-1 and DMM + rhosin groups received intraperitoneal ferroastatin-1 (15 mg/kg) and rhosin (40 mg/kg), respectively, twice/week (21,22), while mice in the control and DMM groups were administered an equivalent volume of normal saline on the same schedule
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